Selenium Experimental Drugs
Selenofolate (available June 2007)
Selenobiotin
Selenodehydrotestosterone
For an explanation of how targeted selenium drugs work, see www.selenbio.com and the following references by Spallholz et al.
On the Nature of Selenium Toxicity and Carcinostatic Activity. Free Radical Biology and Medicine, 17, 45-64, 1994
Preparation of a Cytolytic Selenium Antibody Immunoconjugate. Free Radical Biology and Medicine, 19, 713-724, 1994
Selenium Free Radical Chemistry: Applications for Pharmaceuticals. Proceedings of the 6th International Symposium on Selenium and Tellurium. 47-56, 1998
Selenite, Selenocystamine, and Selenomethionine have Disparate Abilities to Impose Oxidative Stress and Induce Apoptosis in Mouse Keratinocytes. Free Radical Biology and Medicine 26, 42-48, 1999
Dimethyldiselenide and Methylseleninic acid Generate Superoxide in an In Vitro Chemiluminescence?s Assay in the Presence of Glutathione: Implications for the Carcinostatic Activity of L-Selenomethionine and L-Se-Methylselenocysteine. Nutrition and Cancer, 40, 34-41, 2001
Spallholz, J.E., Palace, V.P. and Reid, T.W. Methioninase and Selenomethionine but not Se- Methylselenocysteine Generate Methylselenol and Superoxide in an In Vitro Chemiluminescent Assay: Implications for the Nutritional Carcinostatic Activity of Selenoamino Acids. Biochemical Pharmacology, 67, 547-554, 2004
Experimental drug availability and pricing coming soon. Inquire via phone or email for latest information and pricing.
These items are for research purposes only and only available to universities and research organizations.